SCHEMBL9013848

SCHEMBL9013848

COc1cccc(Cl)n1.Clc1cc(Cl)nc(Cl)n1

nearest known ligand 0.43

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.43
ALDH1A1 P00352 4/20 0.40
HTT P42858 1/20 0.40
HSP90AA1 P07900 3/20 0.38
HSP90AB1 P08238 3/20 0.38
NFE2L2 Q16236 2/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
CNR1 P21554 1/20 0.35
KDM4E B2RXH2 2/20 0.35
HPGD P15428 1/20 0.35
BTK Q06187 1/20 0.35
CYP3A4 P08684 1/20 0.34
TSHR P16473 1/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29427046 0.88
SCHEMBL336762 0.88
Cyanide SCHEMBL28139517 0.82 L3MBTL1 (0.46) L3MBTL1ALDH1A1NFE2L2CNR1BTK
SCHEMBL2339978 0.76 ALDH1A1 (0.47) L3MBTL1ALDH1A1HTTHSP90AA1HSP90AB1
SCHEMBL160602 0.72 BTK (0.47) ALDH1A1KDM4EHPGDBTKTSHR
SCHEMBL959837 0.71 L3MBTL1 (0.62) L3MBTL1ALDH1A1HTTNFE2L2SMN1; SMN2
SCHEMBL6772010 0.70 L3MBTL1 (0.54) L3MBTL1ALDH1A1HTTNFE2L2KDM4E
Ammonia Solution, Strong SCHEMBL27915759 0.69 ALDH1A1 (0.50) L3MBTL1ALDH1A1HSP90AA1HSP90AB1SMN1; SMN2
SCHEMBL218052 0.69
SCHEMBL150750 0.68 ALDH1A1 (0.52) L3MBTL1ALDH1A1HTTSMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0470171-B1 POLYMERIZATION PROCESS AND CATALYST SHELL OIL CO (US) 1996-12-04 EP disclosed