Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 7/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | ABL1 | P00519 | 1/20 | 0.50 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.49 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9014114 | 0.84 | ACHE (0.49) | ACHESMN1; SMN2ABL1RIN1 | |
| SCHEMBL9014137 | 0.79 | HRH1 (0.40) | ACHEHRH3OPRM1 | |
| SCHEMBL9014112 | 0.79 | OPRK1 (0.53) | GAASMN1; SMN2ABL1RIN1HRH3 | |
| SCHEMBL9013995 | 0.78 | GPR119 (0.51) | — | |
| SCHEMBL28597470 | 0.77 | PTGIR (0.56) | ACHEOPRM1LMNA | |
| Hydrochloric Acid SCHEMBL9013903 | 0.74 | SMN1; SMN2 (0.58) | ACHEGAASMN1; SMN2HRH3S1PR5 | |
| SCHEMBL28613676 | 0.74 | ACHE (0.57) | ACHEOPRM1 | |
| SCHEMBL6783771 | 0.74 | ACHE (0.52) | ACHES1PR5KDM4ELMNA | |
| SCHEMBL4237889 | 0.74 | OPRK1 (0.65) | GAASMN1; SMN2HRH3OPRK1LMNA | |
| SCHEMBL13463052 | 0.73 | HRH3 (0.70) | ACHEGAASMN1; SMN2HRH3OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5580883-A | INHIBITING DEGENERATION AND NECROCYTOSIS OF CEREBRAL NERVE CELLS CAUSED BY OXIDATIVE STRESS INDUCING GLUTAMIC ACID IN MAMMALS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-12-03 | — | — | US | disclosed |
| EP-0449195-B1 | Aminobenzene compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1996-05-08 | — | — | EP | disclosed |
| EP-0449195-A2 | Aminobenzene compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1991-10-02 | — | — | EP | disclosed |