Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 6/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11060653 | 0.84 | PTGS2 (0.35) | PTGS2CYP3A4GPR84ALOX5MEN1 | |
| SCHEMBL8800614 | 0.83 | PTGS2 (0.35) | PTGS2CYP3A4GPR84ALOX5MEN1 | |
| SCHEMBL8807946 | 0.83 | PTGS2 (0.35) | PTGS2CYP3A4GPR84KMT2AKDM4E | |
| SCHEMBL5330560 | 0.78 | AR (0.39) | PTGS2CYP3A4GPR84MAPTTSHR | |
| SCHEMBL11300744 | 0.76 | KMT2A (0.33) | CYP3A4GPR84ALOX5MEN1TP53 | |
| SCHEMBL11040456 | 0.76 | KMT2A (0.32) | CYP3A4GPR84ALOX5MEN1TP53 | |
| SCHEMBL12650383 | 0.75 | GPR84 (0.37) | PTGS2CYP3A4GPR84ALOX5MEN1 | |
| SCHEMBL891281 | 0.74 | GPR84 (0.49) | GPR84KMT2A | |
| SCHEMBL891164 | 0.73 | GPR84 (0.51) | CYP3A4GPR84ALOX5MEN1TP53 | |
| SCHEMBL891065 | 0.73 | GPR84 (0.51) | CYP3A4GPR84ALOX5MEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0487870-B1 | Insecticidal and acaricidal diarylpyrrolecarbonitrile and diarylnitropyrrole compounds | AMERICAN CYANAMID CO (US) | 1996-12-18 | — | — | EP | disclosed |
| US-5233052-A | Insecticidal and acaricidal diarylpyrrolecarbonitrile and diarylnitropyrrole compounds | AMERICAN CYANAMID COMPANY (US) | 1993-08-03 | — | — | US | disclosed |
| US-5180734-A | INSECTICIDAL AND ACARICIDAL DIARYLPYRROLECARBONITRILE AND DIARYLNITROPYRROLE COMPOUNDS | AMERICAN CYANAMID COMPANY (US) | 1993-01-19 | — | — | US | disclosed |
| EP-0487870-A2 | Insecticidal and acaricidal diarylpyrrolecarbonitrile and diarylnitropyrrole compounds | AMERICAN CYANAMID COMPANY (US) | 1992-06-03 | — | — | EP | disclosed |