Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.38 |
| ▸ | YAP1 | P46937 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9015673 | 0.84 | CYP3A4 (0.44) | CYP3A4CYP2C19ALDH1A1TSHRYAP1 | |
| SCHEMBL8762111 | 0.82 | CYP3A4 (0.45) | POLBCYP3A4CYP2C19ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL9015591 | 0.81 | CYP3A4 (0.45) | POLBCYP3A4CYP2C19ALDH1A1KDM4E | |
| SCHEMBL7842738 | 0.78 | POLB (0.45) | POLBALDH1A1KDM4ETSHRGPR119 | |
| SCHEMBL7840954 | 0.77 | POLB (0.53) | POLBALDH1A1KDM4ETSHRMEN1 | |
| SCHEMBL7842880 | 0.73 | PKM (0.52) | POLBALDH1A1KDM4ETSHRKMT2A | |
| SCHEMBL8762096 | 0.72 | OPRD1 (0.44) | POLBALDH1A1KDM4ETSHRGPR119 | |
| SCHEMBL8762050 | 0.71 | GPR119 (0.44) | POLBKDM4ETSHRGPR119KMT2A | |
| SCHEMBL9015653 | 0.70 | TSHR (0.42) | POLBKDM4ETSHRGPR119ALOX15 | |
| SCHEMBL9015640 | 0.69 | GPR119 (0.43) | KDM4ETSHRGPR119ALOX15ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5576313-A | ENZYME INHIBITORS AND ANTICARCINOGENIC AGENTS | MERCK & CO., INC. (US) | 1996-11-19 | — | — | US | disclosed |