Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | DRD4 | P21917 | 7/20 | 0.48 |
| ▸ | DRD2 | P14416 | 7/20 | 0.48 |
| ▸ | DRD3 | P35462 | 5/20 | 0.48 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 3/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 3/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3356592 | 0.88 | DRD4 (0.55) | DRD4DRD2DRD3CHRNA7KDM4E | |
| SCHEMBL2937179 | 0.77 | SLC6A2 (0.53) | DRD4DRD2DRD3CHRNA7KDM4E | |
| SCHEMBL2936818 | 0.77 | SLC6A2 (0.53) | DRD4DRD2DRD3CHRNA7KDM4E | |
| SCHEMBL20257559 | 0.73 | CHRM2 (0.43) | KDM4E | |
| SCHEMBL7937213 | 0.72 | HTR1A (0.71) | LMNADRD4DRD2DRD3TSHR | |
| SCHEMBL2935244 | 0.72 | AKR1C3 (0.47) | DRD4DRD2DRD3CHRNA7SIGMAR1 | |
| SCHEMBL12605630 | 0.72 | KCNH2 (0.69) | LMNADRD4DRD2DRD3CHRNA7 | |
| SCHEMBL5022446 | 0.72 | ABCB1 (0.55) | LMNADRD4DRD2DRD3KDM4E | |
| SCHEMBL16142256 | 0.72 | HTR7 (0.59) | DRD4DRD2DRD3CHRNA7KCNH2 | |
| SCHEMBL11084741 | 0.71 | DRD2 (0.67) | DRD4DRD2DRD3CHRNA7KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0441222-B1 | Process and electrode system for determining an analyte or an oxidoreductase as well as suitable compounds | BOEHRINGER MANNHEIM GMBH (DE) | 1996-12-18 | — | — | EP | disclosed |
| US-5286362-A | Reducible substance is enzymatically reduced and oxidized at the electrode; substance formed by oxidation is different from the reducible substance used initially | BOEHRINGER MANNHEIM GMBH (DE) | 1994-02-15 | — | — | US | disclosed |
| US-5122244-A | Having a reducible nitroso or oxime compound to transfer electrons leading to a signal and form an aromatic amine oxidizable to a compound different from the original; low voltage | BOEHRINGER MANNHEIM GMBH (DE) | 1992-06-16 | — | — | US | disclosed |
| EP-0441222-A2 | Process and electrode system for determining an analyte or an oxidoreductase as well as suitable compounds | Roche Diagnostics GmbH (DE) | 1991-08-14 | — | — | EP | disclosed |