SCHEMBL2885813

SCHEMBL2885813

COc1ccc(CN2CCN(CCCSc3cc(C(C)(C)C)c(O)c(C(C)(C)C)c3)CC2)c(OC)c1OC

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CPT1B Q92523 1/20 1.00
TDP1 Q9NUW8 1/20 0.74
MEN1 O00255 7/20 0.55
KMT2A Q03164 7/20 0.55
KDM4E B2RXH2 3/20 0.48
LMNA P02545 3/20 0.48
ALDH1A1 P00352 2/20 0.48
CHRM2 P08172 2/20 0.46
OPRK1 P41145 2/20 0.46
CYP1A2 P05177 1/20 0.46
SLC6A4 P31645 1/20 0.46
OPRD1 P41143 1/20 0.46
PKM P14618 1/20 0.46
APOBEC3A P31941 1/20 0.45
CTDSP1 Q9GZU7 1/20 0.45
APOBEC3G Q9HC16 1/20 0.45
CACNA1G O43497 1/20 0.45
CYP2C19 P33261 1/20 0.44
SMN1; SMN2 Q16637 2/20 0.43
TP53 P04637 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9015998 0.96 CPT1B (0.93) CPT1BTDP1MEN1KMT2AKDM4E
Fumaric Acid SCHEMBL29802140 0.93 CPT1B (0.86) CPT1BTDP1MEN1KMT2AKDM4E
SCHEMBL9015962 0.86 CPT1B (0.75) CPT1BTDP1MEN1KMT2AKDM4E
SCHEMBL9623027 0.85 CPT1B (0.74) CPT1BTDP1MEN1KMT2AKDM4E
SCHEMBL9015995 0.85 CPT1B (0.74) CPT1BTDP1MEN1KMT2AKDM4E
SCHEMBL9015960 0.84 CPT1B (0.73) CPT1BTDP1MEN1KMT2AKDM4E
SCHEMBL9015980 0.84 CPT1B (0.73) CPT1BTDP1MEN1KMT2AKDM4E
SCHEMBL9015974 0.84 CPT1B (0.73) CPT1BTDP1MEN1KMT2AKDM4E
SCHEMBL9015971 0.83 CPT1B (0.70) CPT1BTDP1MEN1KMT2AKDM4E
SCHEMBL9622314 0.82 CPT1B (0.69) CPT1BTDP1MEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240000935-A1 ANTIGEN SPECIFIC T CELLS AND METHODS OF MAKING AND USING SAME GENEIUS BIOTECHNOLOGY, INC. (US) 2024-01-04 US claimed
EP-4251177-A2 ANTIGEN SPECIFIC T CELLS AND METHODS OF MAKING AND USING SAME Geneius Biotechnology, Inc. (US) 2023-10-04 EP claimed
US-20230218608-A1 NEW STRATEGY FOR TREATING PANCREATIC CANCER CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2023-07-13 US claimed
EP-4168006-A1 NEW STRATEGY FOR TREATING PANCREATIC CANCER Institut National de la Santé et de la Recherche Médicale (INSERM) (FR) 2023-04-26 EP claimed
WO-2022115641-A2 ANTIGEN SPECIFIC T CELLS AND METHODS OF MAKING AND USING SAME GENEIUS BIOTECHNOLOGY, INC. (US) 2022-06-02 WO claimed
US-5283246-A Trimetazidine compounds ADIR ET COMPAGNIE (FR) 1994-02-01 US claimed
US-20260076926-A1 COMPOUNDS FOR USE IN ORGAN PRESERVATION AND ORGAN TRANSPLANTATION ABREXA PHARMACEUTICALS, INC. (US) 2026-03-19 US disclosed
US-20250213601-A1 METHODS AND BIOAVAILABLE HIGHLY PERMEABLE COMPOUNDS FOR THE TREATMENT OF VIRAL DISEASES Didenko, Kirill (US) 2025-07-03 US disclosed
CN-110573610-B Method for preparing retinal pigment epithelial cells 住友制药株式会社 2025-01-28 CN disclosed
US-12195779-B2 Methods for harvesting mammalian cell cultures AMGEN INC. (US) 2025-01-14 US disclosed
US-12171821-B2 Toxoplasma gondii vaccine WISCONSIN ALUMNI RESEARCH FOUNDATION (WARF) (US) 2024-12-24 US disclosed
WO-2024189607-A1 METHODS AND BIOAVAILABLE HIGHLY PERMEABLE COMPOUNDS FOR DISEASES TREATMENT DIDENKO KIRILL (MX) 2024-09-19 WO disclosed
EP-4372078-A2 METHODS FOR HARVESTING MAMMALIAN CELL CULTURES Amgen Inc. (US) 2024-05-22 EP disclosed
US-20220136025-A1 METHODS FOR HARVESTING MAMMALIAN CELL CULTURES AMGEN INC. (US) 2022-05-05 US disclosed
US-20100286073-A1 COMPOUNDS AND METHODS FOR PHARMACEUTICAL USE GENERICS (UK) LIMITED (GB) 2010-11-11 US disclosed
EP-2205229-A1 COMPOUNDS AND METHODS FOR PHARMACEUTICAL USE Mintails Limited (CY) 2010-07-14 EP disclosed
WO-2009044202-A1 COMPOUNDS AND METHODS FOR PHARMACEUTICAL USE MINTAILS LIMITED (CY) 2009-04-09 WO disclosed
EP-0533579-B1 Trimetazidine derivatives, process for their preparation and pharmaceutical compositions containing them ADIR (FR) 1996-12-04 EP disclosed
US-5283246-A Trimetazidine compounds ADIR ET COMPAGNIE (FR) 1994-02-01 US disclosed
EP-0533579-A1 Trimetazidine derivatives, process for their preparation and pharmaceutical compositions containing them ADIR ET COMPAGNIE (FR) 1993-03-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260076926-A1 COMPOUNDS FOR USE IN ORGAN PRESERVATION AND ORGAN TRANSPLANTATION CASP9, CASP3, CASP10 CPT1B 196/4885TDP1 2213/4885MEN1 4523/4885
US-20250213601-A1 METHODS AND BIOAVAILABLE HIGHLY PERMEABLE COMPOUNDS FOR THE TREATMENT OF VIRAL DISEASES ACE2, FURIN, SARS1 CPT1B 1897/4885TDP1 1867/4885MEN1 732/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.