Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | ALOX5 | P09917 | 8/20 | 0.56 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9015966 | 0.96 | CPT1B (0.58) | MEN1KMT2AKDM4EALDH1A1LMNA | |
| Fumaric Acid SCHEMBL9296208 | 0.89 | MEN1 (0.54) | MEN1KMT2AKDM4EALDH1A1LMNA | |
| Fumaric Acid SCHEMBL9296210 | 0.89 | MEN1 (0.54) | MEN1KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL9295816 | 0.82 | CPT1B (0.65) | MEN1KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL9015951 | 0.81 | MEN1 (0.55) | MEN1KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL9015968 | 0.81 | LMNA (0.47) | MEN1KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL9015980 | 0.80 | CPT1B (0.73) | MEN1KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL9622306 | 0.80 | ALOX5 (0.47) | MEN1KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL9015994 | 0.80 | SMN1; SMN2 (0.59) | MEN1KMT2AKDM4EALDH1A1ALOX5 | |
| SCHEMBL9016004 | 0.77 | ALOX5 (0.54) | MEN1KMT2AALDH1A1LMNAALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533579-B1 | Trimetazidine derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1996-12-04 | — | — | EP | claimed |
| US-5283246-A | Trimetazidine compounds | ADIR ET COMPAGNIE (FR) | 1994-02-01 | — | — | US | claimed |
| EP-0533579-A1 | Trimetazidine derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1993-03-24 | — | — | EP | claimed |
| EP-0533579-B1 | Trimetazidine derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1996-12-04 | — | — | EP | disclosed |
| US-5283246-A | Trimetazidine compounds | ADIR ET COMPAGNIE (FR) | 1994-02-01 | — | — | US | disclosed |
| EP-0533579-A1 | Trimetazidine derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1993-03-24 | — | — | EP | disclosed |