Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 8/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 4/20 | 0.41 |
| ▸ | HTR7 | P34969 | 4/20 | 0.41 |
| ▸ | HTR1A | P08908 | 4/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.41 |
| ▸ | BCL9 | O00512 | 1/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.40 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.40 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | EBP | Q15125 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9015994 | 0.83 | SMN1; SMN2 (0.59) | ALOX5MEN1ALDH1A1KMT2AKCNH2 | |
| SCHEMBL9015966 | 0.81 | CPT1B (0.58) | ALOX5MEN1ALDH1A1KMT2ALMNA | |
| SCHEMBL9015965 | 0.77 | MEN1 (0.57) | ALOX5MEN1ALDH1A1KMT2ALMNA | |
| Fumaric Acid SCHEMBL9296210 | 0.74 | MEN1 (0.54) | ALOX5MEN1ALDH1A1KMT2ALMNA | |
| Fumaric Acid SCHEMBL9296208 | 0.74 | MEN1 (0.54) | ALOX5MEN1ALDH1A1KMT2ALMNA | |
| SCHEMBL9622306 | 0.69 | ALOX5 (0.47) | ALOX5MEN1ALDH1A1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL2193293 | 0.67 | ALOX5 (1.00) | ALOX5MEN1ALDH1A1KMT2A | |
| SCHEMBL9380612 | 0.67 | ALOX5 (0.49) | ALOX5ALDH1A1KMT2AHTR2AHTR1A | |
| SCHEMBL27857935 | 0.67 | ALDH1A1 (0.50) | MEN1ALDH1A1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL5546075 | 0.66 | GAA (0.52) | MEN1ALDH1A1KMT2ADRD2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533579-B1 | Trimetazidine derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1996-12-04 | — | — | EP | disclosed |
| EP-0533579-A1 | Trimetazidine derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1993-03-24 | — | — | EP | disclosed |