SCHEMBL9016415

SCHEMBL9016415

CCc1nc2c(C)cc(C)nc2n1-c1ccc(-c2ccccc2C#N)cc1

nearest known ligand 0.48

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AGTR1 P30556 3/20 0.46
AGTR2 P50052 3/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9016428 0.93 PPARG (0.47) AGTR1AGTR2
SCHEMBL9016503 0.91 AGTR1 (0.48) AGTR1AGTR2
SCHEMBL9016524 0.84 PPARG (0.41) AGTR1
SCHEMBL7387302 0.84 AGTR1 (0.65) AGTR1AGTR2
SCHEMBL8872253 0.82 AGTR1 (0.43) AGTR1AGTR2
SCHEMBL9016540 0.82 PPARG (0.39) AGTR1
SCHEMBL9016411 0.82 SLC6A9 (0.40)
SCHEMBL8872834 0.79 AGTR1 (0.66) AGTR1AGTR2
SCHEMBL9016422 0.77 PPARG (0.48) AGTR1AGTR2
SCHEMBL8873335 0.77 AGTR1 (0.47) AGTR1AGTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5554757-A Process for the preparation of imidazopyridine derivatives, and intermediates therefore EISAI CO., LTD. (JP) 1996-09-10 US disclosed