SCHEMBL9016725

SCHEMBL9016725

CSc1cc(=O)c2cc(OC(=O)OC(C)(C)C)c(OC(=O)OC(C)(C)C)cc2s1

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.33
ELANE P08246 1/20 0.33
STING1 Q86WV6 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9016576 0.82 ELANE (0.34) CA2ELANESTING1
SCHEMBL9016666 0.80 MTNR1A (0.31)
SCHEMBL9016767 0.79 CUL4A (0.31)
SCHEMBL9016635 0.77 MTNR1A (0.32) CA2ELANESTING1
SCHEMBL9016620 0.76 MAOA (0.44) STING1
SCHEMBL9016762 0.68 CA2 (0.30) CA2
SCHEMBL15839314 0.65 RAB9A (0.46) CA2STING1
SCHEMBL7774018 0.61 ALDH1A1 (0.41)
SCHEMBL9016727 0.61 TSHR (0.38)
SCHEMBL7777262 0.61 MAPT (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0481441-B1 Novel cephem compounds, their preparation processes and antibacterial agents KYORIN SEIYAKU KK (JP) 1996-12-11 EP disclosed
US-5244892-A Pseudomonas KYORIN PHARMACEUTICAL CO., LTD. (JP) 1993-09-14 US disclosed
EP-0481441-A2 Novel cephem compounds, their preparation processes and antibacterial agents KYORIN PHARMACEUTICAL CO., LTD. (JP) 1992-04-22 EP disclosed