Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP2 | O95551 | 3/20 | 0.64 |
| ▸ | BRAF | P15056 | 3/20 | 0.56 |
| ▸ | CHEK1 | O14757 | 9/20 | 0.53 |
| ▸ | WEE1 | P30291 | 9/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.44 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 3/20 | 0.43 |
| ▸ | STK10 | O94804 | 1/20 | 0.43 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29652041 | 1.00 | TDP2 (0.64) | TDP2BRAFCHEK1WEE1KDM4E | |
| SCHEMBL9016868 | 0.87 | GSK3B (0.50) | TDP2BRAFCHEK1WEE1KDM4E | |
| SCHEMBL2894929 | 0.82 | ALDH1A1 (0.46) | TDP2CHEK1WEE1KDM4EALDH1A1 | |
| SCHEMBL8757366 | 0.82 | WEE1 (0.50) | TDP2BRAFCHEK1WEE1 | |
| SCHEMBL16754925 | 0.81 | GSK3B (0.62) | TDP2BRAFKDM4EALDH1A1GAA | |
| SCHEMBL8006987 | 0.81 | TDP2 (0.48) | TDP2BRAFCHEK1WEE1 | |
| SCHEMBL135332 | 0.80 | GSK3B (0.56) | TDP2CHEK1WEE1KDM4EALDH1A1 | |
| SCHEMBL10947949 | 0.79 | PPOX (0.50) | TDP2KDM4EALDH1A1GAAHPGD | |
| SCHEMBL18010805 | 0.79 | TDP2 (1.00) | TDP2BRAFCHEK1WEE1CYP3A4 | |
| SCHEMBL29032840 | 0.78 | GSK3B (0.54) | TDP2CHEK1WEE1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114163450-B | Thermochromic material with single rhodamine structure, developing composition, preparation method and application thereof | 北京高德品创科技有限公司 | 2022-05-06 | — | — | CN | disclosed |
| CN-114163450-A | Thermochromic material with single rhodamine structure, developing composition, preparation method and application thereof | 北京高德品创科技有限公司 | 2022-03-11 | — | — | CN | disclosed |