SCHEMBL9017183

SCHEMBL9017183

CCCP(I)(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.35
KCNH2 Q12809 1/20 0.30
PSIP1 O75475 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18270036 0.86 LTA4H (0.35)
SCHEMBL14787941 0.85 LTA4H (0.36) TP53KCNH2
SCHEMBL26404626 0.84 SOAT2 (0.33)
SCHEMBL28555187 0.83 DNM1 (0.38) TP53KCNH2
SCHEMBL28945192 0.83 DNM1 (0.38) TP53KCNH2
SCHEMBL4951520 0.80 TP53 (0.38) TP53PSIP1
SCHEMBL29025756 0.80 EPHX2 (0.34)
SCHEMBL9317971 0.75 TP53 (0.43) TP53
SCHEMBL5818573 0.75 TP53 (0.38) TP53PSIP1
SCHEMBL5289246 0.73 TP53 (0.36) TP53PSIP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117603160-A Synthesis method of high-purity tebuthiuron 山东华阳农药化工集团有限公司 2024-02-27 CN claimed
CN-117603160-A Synthesis method of high-purity tebuthiuron 山东华阳农药化工集团有限公司 2024-02-27 CN disclosed
US-20170369418-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT JNC CORPORATION (JP) 2017-12-28 US disclosed
US-20140315956-A1 SMALL MOLECULE INHIBITORS OF IL-6 AND USES THEREOF NATIONWIDE CHILDREN'S HOSPITAL (US) 2014-10-23 US disclosed
US-20140315956-A1 SMALL MOLECULE INHIBITORS OF IL-6 AND USES THEREOF NATIONWIDE CHILDREN'S HOSPITAL (US) 2014-10-23 US disclosed
WO-2013019690-A1 SMALL MOLECULE INHIBITORS OF IL-6 AND USES THEREOF THE OHIO STATE UNIVERSITY (US) 2013-02-07 WO disclosed
EP-0750028-A2 Alkenylcyclohexane derivatives, liquid crystal composition and liquid crystal display element Chisso Corporation (JP) 1996-12-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140315956-A1 SMALL MOLECULE INHIBITORS OF IL-6 AND USES THEREOF IL6, STAT3, JAK2 TP53 343/4885KCNH2 3997/4885PSIP1 2234/4885
US-20170369418-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT SP1, SPIN1, SAV1 TP53 1968/4885KCNH2 373/4885PSIP1 367/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.