SCHEMBL9017304

SCHEMBL9017304

N#Cc1c(Cl)c(C(F)(F)F)n(CN(CC(=O)O)C(=O)c2ccccc2)c1-c1ccc(Cl)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.36
MAPT P10636 2/20 0.36
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
GPBAR1 Q8TDU6 1/20 0.35
ALDH1A1 P00352 5/20 0.34
NPC1 O15118 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
CNR1 P21554 1/20 0.34
ADORA2A P29274 1/20 0.33
ADORA1 P30542 1/20 0.33
CTSL P07711 1/20 0.33
CTSS P25774 1/20 0.33
KDM4E B2RXH2 4/20 0.32
CNR2 P34972 1/20 0.32
CHRM2 P08172 1/20 0.32
CHRM3 P20309 1/20 0.32
HPGD P15428 5/20 0.32
GAA P10253 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9422643 0.96 ALDH1A1 (0.38) POLBMAPTMEN1KMT2ATDP1
SCHEMBL9017388 0.87 POLB (0.37) POLBMAPTMEN1KMT2ATDP1
SCHEMBL9017291 0.81 DAGLA (0.39) POLBMAPTMEN1KMT2ATDP1
SCHEMBL9017309 0.74 KMT2A (0.49) POLBMAPTMEN1KMT2AALDH1A1
SCHEMBL7494704 0.73 KDM4E (0.39) POLBMAPTMEN1KMT2AALDH1A1
SCHEMBL9460809 0.72 POLB (0.39) POLBMAPTMEN1KMT2ATDP1
SCHEMBL9036743 0.72 KDM4E (0.38) POLBMAPTMEN1KMT2AALDH1A1
SCHEMBL8994385 0.72 POLB (0.37) POLBMAPTMEN1KMT2ATDP1
SCHEMBL9460811 0.71 POLB (0.37) POLBMAPTMEN1KMT2ATDP1
SCHEMBL8994400 0.71 POLB (0.36) POLBMAPTMEN1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0594942-B1 N-aminoalkylcarbonyloxyalkylpyrrole insecticidal acaricidal and molluscicidal agents AMERICAN CYANAMID CO (US) 1996-09-04 EP claimed