Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL901370 | 0.87 | KARS1 (0.45) | KARS1SYK | |
| SCHEMBL901369 | 0.87 | KARS1 (0.45) | KARS1SYK | |
| SCHEMBL901752 | 0.85 | KARS1 (0.73) | KARS1 | |
| SCHEMBL12469691 | 0.81 | KARS1 (0.72) | KARS1 | |
| SCHEMBL12469310 | 0.81 | KARS1 (0.56) | KARS1SYK | |
| SCHEMBL901333 | 0.77 | KARS1 (0.65) | KARS1SYK | |
| SCHEMBL901761 | 0.75 | KARS1 (0.54) | KARS1 | |
| SCHEMBL1704272 | 0.75 | KARS1 (0.74) | KARS1 | |
| SCHEMBL902051 | 0.74 | KARS1 (0.55) | KARS1SYK | |
| SCHEMBL902003 | 0.74 | KARS1 (0.61) | KARS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012041476-A1 | PYRIDINE AND ISOQUINOLINE DERIVATIVES AS SYK- AND JAK-KINASE INHIBITORS | ALMIRALL, S.A. (ES) | 2012-04-05 | — | — | WO | disclosed |