Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.44 |
| ▸ | NOS1 | P29475 | 1/20 | 0.44 |
| ▸ | NOS2 | P35228 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 5/20 | 0.37 |
| ▸ | SLC1A3 | P43003 | 4/20 | 0.37 |
| ▸ | SLC1A2 | P43004 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.34 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.33 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.33 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.33 |
| ▸ | GRIK3 | Q13003 | 2/20 | 0.33 |
| ▸ | GRIK5 | Q16478 | 2/20 | 0.33 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.33 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2200757 | 0.80 | SLC7A5 (0.52) | SLC7A5TSHRSLC1A1SLC1A3SLC1A2 | |
| SCHEMBL14043512 | 0.80 | SLC7A5 (0.52) | SLC7A5TSHRSLC1A1SLC1A3SLC1A2 | |
| SCHEMBL11912087 | 0.78 | MAPT (0.43) | MAPTTSHRLMNA | |
| SCHEMBL11115364 | 0.77 | LMNA (0.46) | MAPTTSHRLMNA | |
| SCHEMBL13857278 | 0.76 | NOS2 (0.53) | NOS3NOS1NOS2SLC7A5TSHR | |
| SCHEMBL12028657 | 0.76 | NOS2 (0.53) | NOS3NOS1NOS2SLC7A5TSHR | |
| SCHEMBL4156927 | 0.76 | NOS2 (0.47) | NOS3NOS1NOS2SLC7A5TSHR | |
| SCHEMBL6274592 | 0.76 | NOS2 (0.47) | NOS3NOS1NOS2SLC7A5TSHR | |
| SCHEMBL4156931 | 0.76 | NOS2 (0.47) | NOS3NOS1NOS2SLC7A5TSHR | |
| SCHEMBL17434420 | 0.75 | NOS3 (0.53) | NOS3NOS1NOS2SLC7A5SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0414632-B1 | Cyclosporin derivatives | SANDOZ LTD (CH) | 1996-10-23 | — | — | EP | claimed |
| EP-0414632-B1 | Cyclosporin derivatives | SANDOZ LTD (CH) | 1996-10-23 | — | — | EP | disclosed |