Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 4/20 | 0.54 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 9/20 | 0.41 |
| ▸ | BRAF | P15056 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | G6PD | P11413 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9017547 | 0.86 | DHODH (0.61) | DHODHALDH1A1MAPTMEN1G6PD | |
| SCHEMBL9017561 | 0.86 | DHODH (0.61) | DHODHMTNR1AMTNR1BALDH1A1MAPT | |
| SCHEMBL9017582 | 0.84 | DHODH (0.52) | DHODHPLA2G7KDRBRAFMAPT | |
| SCHEMBL9017570 | 0.83 | DHODH (0.61) | DHODHMTNR1AMTNR1BALDH1A1MAPT | |
| SCHEMBL9017598 | 0.83 | DHODH (0.43) | DHODHKDRBRAFALDH1A1MAPT | |
| SCHEMBL9157076 | 0.83 | DHODH (0.64) | DHODHMTNR1AMTNR1BALDH1A1MAPT | |
| SCHEMBL9017532 | 0.82 | DHODH (0.55) | DHODHMTNR1AMTNR1BALDH1A1MAPT | |
| SCHEMBL9017556 | 0.82 | DHODH (0.49) | DHODHPLA2G7KDRBRAFMAPT | |
| SCHEMBL9017576 | 0.81 | DHODH (0.69) | DHODHMTNR1AMTNR1BALDH1A1MAPT | |
| SCHEMBL9017543 | 0.81 | DHODH (0.65) | DHODHALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533573-B1 | Derivatives of 3-cyclo alkyl-propen-2-amide, their tautomeres and salts and their use as antiinflammatory agents | ROUSSEL UCLAF (FR) | 1996-12-04 | — | — | EP | disclosed |
| US-5389652-A | Antiinflammatory agent | ROUSSEL-UCLAF (FR) | 1995-02-14 | — | — | US | disclosed |
| US-5312830-A | Antiinflammatory agents | ROUSSEL-UCLAF (FR) | 1994-05-17 | — | — | US | disclosed |
| EP-0533573-A2 | Derivatives of 3-cyclo alkyl-propen-2-amide, their tautomeres and salts and their use as antiinflammatory agents | ROUSSEL UCLAF (FR) | 1993-03-24 | — | — | EP | disclosed |