Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | NCEH1 | Q6PIU2 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9017860 | 1.00 | BCHE (0.38) | BCHEMAOAACHEMAOBNCEH1 | |
| SCHEMBL9017889 | 0.99 | ACHE (0.39) | BCHEMAOAACHEMAOBNCEH1 | |
| SCHEMBL9017892 | 0.99 | ACHE (0.39) | BCHEMAOAACHEMAOBNCEH1 | |
| SCHEMBL9017875 | 0.99 | ACHE (0.39) | BCHEMAOAACHEMAOBNCEH1 | |
| SCHEMBL9017879 | 0.99 | ACHE (0.39) | BCHEMAOAACHEMAOBNCEH1 | |
| SCHEMBL9017869 | 0.92 | NCEH1 (0.33) | BCHEMAOAACHEMAOBNCEH1 | |
| SCHEMBL9017868 | 0.92 | NCEH1 (0.33) | BCHEMAOAACHEMAOBNCEH1 | |
| SCHEMBL9017878 | 0.91 | GAA (0.37) | NCEH1RAB9ATSHRKDM4EALDH1A1 | |
| SCHEMBL9017874 | 0.91 | GAA (0.37) | NCEH1RAB9ATSHRKDM4EALDH1A1 | |
| SCHEMBL9017846 | 0.82 | RAB9A (0.38) | BCHENCEH1RAB9APKMNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0477903-B1 | Substituted-4-amino-3-pyridinols, a process for their preparation and their use as medicaments | HOECHST ROUSSEL PHARMA (US) | 1996-04-03 | — | — | EP | disclosed |
| EP-0477903-A2 | Substituted-4-amino-3-pyridinols, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1992-04-01 | — | — | EP | disclosed |