Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 2/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | KDM5A | P29375 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9017908 | 1.00 | KDM4E (0.39) | KDM4EKMT2AGAAMEN1MAPT | |
| SCHEMBL9017886 | 0.87 | KDM4E (0.36) | KDM4EKMT2AGAAL3MBTL1ALDH1A1 | |
| SCHEMBL9017883 | 0.87 | KDM4E (0.36) | KDM4EKMT2AGAAL3MBTL1ALDH1A1 | |
| SCHEMBL9017866 | 0.85 | MEN1 (0.41) | KDM4EKMT2AMEN1MAPTL3MBTL1 | |
| SCHEMBL9017862 | 0.85 | MEN1 (0.41) | KDM4EKMT2AMEN1MAPTL3MBTL1 | |
| SCHEMBL9017843 | 0.84 | RAB9A (0.38) | KDM4EGAAL3MBTL1ALDH1A1LMNA | |
| SCHEMBL9017846 | 0.84 | RAB9A (0.38) | KDM4EGAAL3MBTL1ALDH1A1LMNA | |
| SCHEMBL9017844 | 0.82 | HSP90AA1 (0.42) | KDM4EKMT2AGAAMEN1MAPT | |
| SCHEMBL9017842 | 0.82 | HSP90AA1 (0.42) | KDM4EKMT2AGAAMEN1MAPT | |
| SCHEMBL9679849 | 0.79 | LIPE (0.40) | KDM4EKMT2AGAAMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0477903-B1 | Substituted-4-amino-3-pyridinols, a process for their preparation and their use as medicaments | HOECHST ROUSSEL PHARMA (US) | 1996-04-03 | — | — | EP | disclosed |