Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ALB | P02768 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 3/20 | 0.42 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9018169 | 0.96 | CA2 (0.50) | ALDH1A1CYP2C9LMNAALBTSHR | |
| SCHEMBL9018436 | 0.92 | CA2 (0.46) | ALDH1A1CYP2C9LMNAALBTSHR | |
| SCHEMBL9018266 | 0.92 | HPGD (0.47) | ALDH1A1LMNAEGFRP4HTMKDM4E | |
| SCHEMBL9018050 | 0.90 | P4HTM (0.44) | ALDH1A1TP53EGFRP4HTMKDM4E | |
| SCHEMBL9018017 | 0.90 | EGFR (0.45) | EGFRP4HTMKMT2ASMN1; SMN2 | |
| SCHEMBL9018204 | 0.90 | NPC1 (0.46) | ALDH1A1P4HTMKDM4ENPC1RAB9A | |
| SCHEMBL9017994 | 0.89 | EGFR (0.41) | ALDH1A1CA2EGFRP4HTMKDM4E | |
| SCHEMBL9018404 | 0.89 | EGLN1 (0.45) | ALDH1A1CYP2C9LMNAALBTSHR | |
| SCHEMBL9018027 | 0.88 | CA2 (0.52) | ALDH1A1CYP2C9LMNAALBTSHR | |
| SCHEMBL9018148 | 0.88 | CA2 (0.42) | ALDH1A1CYP2C9LMNAALBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0590520-B1 | Acylsulphonamido and sulphonamidopyridine-2-carboxylic acid esters, pyridine-n-oxides thereof, a process for their preparation and their use as medicaments | HOECHST AG (DE) | 1996-06-12 | — | — | EP | disclosed |
| EP-0590520-A1 | Acylsulphonamido and sulphonamidopyridine-2-carboxylic acid esters, pyridine-n-oxides thereof, a process for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-04-06 | — | — | EP | disclosed |