Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MLYCD | O95822 | 1/20 | 0.39 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALB | P02768 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9018148 | 0.96 | CA2 (0.42) | CA2RXFP1NPC1RAB9AP4HTM | |
| SCHEMBL9018082 | 0.94 | CA2 (0.47) | CA2L3MBTL1NAAARXFP1NPC1 | |
| SCHEMBL9018392 | 0.92 | CA2 (0.48) | CA2L3MBTL1NAAARXFP1NPC1 | |
| SCHEMBL9018027 | 0.92 | CA2 (0.52) | CA2L3MBTL1NAAARXFP1NPC1 | |
| SCHEMBL9018053 | 0.91 | CA2 (0.40) | CA2L3MBTL1NAAARXFP1P4HTM | |
| SCHEMBL9018422 | 0.90 | CA2 (0.41) | CA2NPC1RAB9AP4HTMEGFR | |
| SCHEMBL9018499 | 0.90 | OPRK1 (0.44) | NPC1RAB9AMLYCDP4HTMOPRK1 | |
| SCHEMBL9018370 | 0.90 | KMT2A (0.45) | L3MBTL1NPC1RAB9AP4HTMEGFR | |
| SCHEMBL9018203 | 0.89 | EGFR (0.42) | NPC1RAB9AP4HTMEGFROPRK1 | |
| SCHEMBL9018142 | 0.89 | NPC1 (0.45) | NPC1RAB9AMLYCDP4HTMOPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0590520-B1 | Acylsulphonamido and sulphonamidopyridine-2-carboxylic acid esters, pyridine-n-oxides thereof, a process for their preparation and their use as medicaments | HOECHST AG (DE) | 1996-06-12 | — | — | EP | disclosed |
| EP-0590520-A1 | Acylsulphonamido and sulphonamidopyridine-2-carboxylic acid esters, pyridine-n-oxides thereof, a process for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-04-06 | — | — | EP | disclosed |