Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.40 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31401027 | 0.89 | CDC25B (0.45) | CDC25BPKMPOLBKMT2AMEN1 | |
| SCHEMBL8610270 | 0.87 | SLC9A1 (0.55) | — | |
| SCHEMBL9018715 | 0.82 | SLC9A1 (0.59) | — | |
| SCHEMBL17908014 | 0.79 | ABCB11 (0.45) | CDC25BPKMPOLBKMT2AMEN1 | |
| SCHEMBL5405584 | 0.77 | CDC25B (0.53) | CDC25BPKMPOLBKMT2ASMN1; SMN2 | |
| SCHEMBL9018704 | 0.76 | SLC9A1 (0.41) | — | |
| SCHEMBL2593426 | 0.76 | PTK2B (0.58) | CDC25BPKMKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL27373161 | 0.75 | CDC25B (0.41) | CDC25BPKMPOLBKMT2AMEN1 | |
| SCHEMBL9018673 | 0.75 | PKM (0.50) | CDC25BPKMPOLBPTK2BNPSR1 | |
| SCHEMBL29586404 | 0.74 | AR (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0743301-A2 | Benzoylguanidines containing fluorine | MERCK PATENT GmbH (DE) | 1996-11-20 | — | — | EP | disclosed |