Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | SLC9A1 | P19634 | 3/20 | 0.46 |
| ▸ | PLAU | P00749 | 3/20 | 0.45 |
| ▸ | CES2 | O00748 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | CFTR | P13569 | 1/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.40 |
| ▸ | HTR3B | O95264 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.40 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8393386 | 0.98 | GAA (0.50) | GAAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8609955 | 0.89 | CFTR (0.57) | GAAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9018707 | 0.87 | SLC9A1 (0.46) | GAAKDM4EALDH1A1HPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL8393445 | 0.86 | SLC9A1 (0.45) | GAAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9018716 | 0.84 | CES2 (0.62) | KDM4EALDH1A1HPGDHSD17B10SLC9A1 | |
| SCHEMBL2920377 | 0.81 | DGAT1 (0.56) | GAAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9018662 | 0.81 | CES2 (0.62) | KDM4EALDH1A1HPGDHSD17B10SLC9A1 | |
| SCHEMBL9018705 | 0.79 | SLC9A1 (0.48) | SLC9A1PLAUCES2 | |
| Hydrochloric Acid SCHEMBL8393438 | 0.79 | CES2 (0.60) | KDM4EALDH1A1HPGDHSD17B10SLC9A1 | |
| SCHEMBL9018689 | 0.79 | JAK2 (0.48) | KDM4EALDH1A1HPGDHSD17B10SLC9A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0743301-A2 | Benzoylguanidines containing fluorine | MERCK PATENT GmbH (DE) | 1996-11-20 | — | — | EP | disclosed |