SCHEMBL9018700

SCHEMBL9018700

Cc1cc(OCF)c(S(C)(=O)=O)cc1C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SLC9A1 P19634 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8610222 0.88 SLC9A1 (0.61) SLC9A1
SCHEMBL9018724 0.81 SLC9A1 (0.67) SLC9A1
SCHEMBL8442834 0.81 RXRA (0.50)
SCHEMBL9018709 0.79 SLC9A1 (0.39) SLC9A1
SCHEMBL7797862 0.79 EGLN1 (0.43) SLC9A1
SCHEMBL9018714 0.78 PKM (0.50)
SCHEMBL5190885 0.77 SLC9A1 (0.59) SLC9A1
SCHEMBL8059436 0.75 NR1H4 (0.46)
SCHEMBL8440231 0.75 CYP1A2 (0.43)
SCHEMBL7764035 0.74 SLC9A1 (0.45) SLC9A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0743301-A2 Benzoylguanidines containing fluorine MERCK PATENT GmbH (DE) 1996-11-20 EP disclosed