Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | RPA1 | P27694 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CTRC | Q99895 | 2/20 | 0.40 |
| ▸ | PPP1CA | P62136 | 2/20 | 0.40 |
| ▸ | RXRA | P19793 | 2/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | CDH1 | P12830 | 1/20 | 0.39 |
| ▸ | APC | P25054 | 1/20 | 0.39 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.39 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34469690 | 0.80 | TSHR (0.47) | ALOX15TSHRRPA1SMN1; SMN2CTRC | |
| SCHEMBL9019021 | 0.78 | ALOX15 (0.48) | ALOX15TSHRRPA1SMN1; SMN2CTRC | |
| SCHEMBL8937617 | 0.71 | SMN1; SMN2 (0.41) | ALOX15TSHRSMN1; SMN2L3MBTL1EGLN1 | |
| SCHEMBL34469830 | 0.70 | CYP1A2 (0.48) | TSHRSMN1; SMN2L3MBTL1CHRNA7 | |
| SCHEMBL9019058 | 0.69 | LMNA (0.46) | ALOX15TSHRRPA1SMN1; SMN2PPP1CA | |
| SCHEMBL2041424 | 0.66 | TSHR (0.85) | ALOX15TSHRSMN1; SMN2CTRCRXRA | |
| 4-Chloro-Benzoic Acid SCHEMBL379139 | 0.66 | TSHR (0.94) | ALOX15TSHRSMN1; SMN2RXRARXRB | |
| SCHEMBL8628997 | 0.65 | TPMT (0.74) | ALOX15TSHRCTRCRXRARXRB | |
| SCHEMBL491622 | 0.65 | RXRA (0.64) | ALOX15TSHRCTRCRXRARXRB | |
| SCHEMBL3381195 | 0.65 | ACLY (0.51) | ALOX15TSHRCTRCRXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0434940-B1 | N-oxygenated arylpyrrole, insecticidal, acaricidal and nematicidal agents | AMERICAN CYANAMID CO (US) | 1996-05-29 | — | — | EP | disclosed |
| US-5399716-A | N-oxygenated arylpyrrole insecticidal, acaricidal and nematicidal agents | AMERICAN CYANAMID COMPANY (US) | 1995-03-21 | — | — | US | disclosed |
| US-5347016-A | N-oxygenated arylpyrrole intermediates for insecticidal, acaricidal and nematicidal agents | AMERICAN CYANAMID COMPANY (US) | 1994-09-13 | — | — | US | disclosed |
| US-5232979-A | Insecticides, miticides, nematocides | AMERICAN CYANAMID COMPANY (US) | 1993-08-03 | — | — | US | disclosed |
| US-5102904-A | N-OXYGENATED ARYLPYRROLE INSECTICIDAL, ACARICIDAL AND NEMATICIDAL AGENTS AND USE THEREAS | AMERICAN CYANAMID COMPANY (US) | 1992-04-07 | — | — | US | disclosed |
| EP-0434940-A2 | N-oxygenated arylpyrrole, insecticidal, acaricidal and nematicidal agents | AMERICAN CYANAMID COMPANY (US) | 1991-07-03 | — | — | EP | disclosed |