Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.45 |
| ▸ | MAOA | P21397 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8937646 | 0.75 | MAOA (0.39) | MAOBMAOAALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL9019106 | 0.63 | MAOB (0.41) | MAOBMAOAALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL5012020 | 0.57 | ALDH1A1 (0.46) | ALDH1A1LMNASMN1; SMN2KDM4EHPGD | |
| SCHEMBL18204411 | 0.57 | ALDH1A1 (0.50) | MAOBMAOAALDH1A1LMNASMN1; SMN2 | |
| Biphenyl SCHEMBL28931658 | 0.57 | ALDH1A1 (0.60) | MAOAALDH1A1SMN1; SMN2KDM4EHPGD | |
| Biphenyl SCHEMBL1153864 | 0.57 | ALDH1A1 (0.60) | MAOAALDH1A1SMN1; SMN2KDM4EHPGD | |
| Biphenyl SCHEMBL28657752 | 0.57 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2BACE1CYP1A1CYP1A2 | |
| Biphenyl SCHEMBL29145978 | 0.57 | ALDH1A1 (0.60) | MAOAALDH1A1SMN1; SMN2KDM4EHPGD | |
| Benzonitrile SCHEMBL16468987 | 0.56 | TSHR (0.78) | MAOBMAOAALDH1A1SMN1; SMN2 | |
| SCHEMBL25159291 | 0.56 | MAPK1 (0.56) | ALDH1A1LMNASMN1; SMN2KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0434940-B1 | N-oxygenated arylpyrrole, insecticidal, acaricidal and nematicidal agents | AMERICAN CYANAMID CO (US) | 1996-05-29 | — | — | EP | disclosed |
| US-5399716-A | N-oxygenated arylpyrrole insecticidal, acaricidal and nematicidal agents | AMERICAN CYANAMID COMPANY (US) | 1995-03-21 | — | — | US | disclosed |
| US-5347016-A | N-oxygenated arylpyrrole intermediates for insecticidal, acaricidal and nematicidal agents | AMERICAN CYANAMID COMPANY (US) | 1994-09-13 | — | — | US | disclosed |
| US-5232979-A | Insecticides, miticides, nematocides | AMERICAN CYANAMID COMPANY (US) | 1993-08-03 | — | — | US | disclosed |
| US-5102904-A | N-OXYGENATED ARYLPYRROLE INSECTICIDAL, ACARICIDAL AND NEMATICIDAL AGENTS AND USE THEREAS | AMERICAN CYANAMID COMPANY (US) | 1992-04-07 | — | — | US | disclosed |
| EP-0434940-A2 | N-oxygenated arylpyrrole, insecticidal, acaricidal and nematicidal agents | AMERICAN CYANAMID COMPANY (US) | 1991-07-03 | — | — | EP | disclosed |