SCHEMBL9703660

SCHEMBL9703660

COn1c(C#N)cc(Br)c1-c1ccc(Cl)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AR P10275 1/20 0.51
MAOB P27338 3/20 0.41
RAB9A P51151 3/20 0.40
KMT2A Q03164 3/20 0.40
MAPT P10636 2/20 0.40
MEN1 O00255 2/20 0.40
ALDH1A1 P00352 5/20 0.35
KDM4E B2RXH2 4/20 0.35
GAA P10253 2/20 0.35
SQOR Q9Y6N5 1/20 0.34
MAOA P21397 8/20 0.34
NPC1 O15118 2/20 0.33
HPGD P15428 2/20 0.33
MCL1 Q07820 1/20 0.33
CASP3 P42574 1/20 0.33
SENP8 Q96LD8 1/20 0.33
SENP7 Q9BQF6 1/20 0.33
SENP6 Q9GZR1 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9019009 0.75 MAOB (0.45) MAOBRAB9AKMT2AMAPTMEN1
SCHEMBL9019106 0.73 MAOB (0.41) MAOBRAB9AKMT2AMAPTMEN1
SCHEMBL9019084 0.73 MAOB (0.44) MAOBRAB9AKMT2AMAPTMEN1
SCHEMBL9702833 0.72 KDM4E (0.45) ARRAB9AKMT2AMAPTMEN1
SCHEMBL9019130 0.70 USP2 (0.38) MAOBRAB9AKMT2AMAPTMEN1
SCHEMBL9316669 0.67 AR (0.36) ARMAOBKMT2AMEN1ALDH1A1
SCHEMBL9019069 0.66 ALDH1A1 (0.46) MAOBRAB9AKMT2AMAPTMEN1
SCHEMBL9019083 0.65 KDM4E (0.43) MAOBKMT2AMAPTMEN1ALDH1A1
SCHEMBL9019127 0.64 MAOB (0.43) ARMAOBMAPTALDH1A1MAOA
SCHEMBL9019128 0.64 KDM4E (0.42) RAB9AKMT2AMAPTMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5102904-A N-OXYGENATED ARYLPYRROLE INSECTICIDAL, ACARICIDAL AND NEMATICIDAL AGENTS AND USE THEREAS AMERICAN CYANAMID COMPANY (US) 1992-04-07 US claimed