Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL704144 | 0.73 | ATM (0.39) | LMNA | |
| SCHEMBL503802 | 0.72 | POLB (0.70) | ALDH1A1KDM4EHPGDPOLBMEN1 | |
| SCHEMBL8572013 | 0.71 | KDM4E (0.69) | ALDH1A1KDM4EHPGDPOLBHSD11B1 | |
| SCHEMBL9185042 | 0.70 | POLB (0.68) | ALDH1A1KDM4EHPGDPOLBMEN1 | |
| SCHEMBL9810575 | 0.69 | ALDH1A1 (0.53) | ALDH1A1KDM4EHPGDPOLBMEN1 | |
| SCHEMBL9020526 | 0.68 | KDM4E (0.49) | ALDH1A1KDM4EHPGDPOLBMEN1 | |
| SCHEMBL987280 | 0.67 | KDM4E (0.51) | ALDH1A1KDM4EHPGDPOLBNPSR1 | |
| SCHEMBL20561321 | 0.67 | KMT2A (0.42) | KMT2AMAPK1LMNA | |
| SCHEMBL712706 | 0.67 | CTSV (0.60) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL9056011 | 0.67 | MAPT (0.53) | ALDH1A1KDM4EPOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532138-A | Method and kits for determining peroxidatively active catalysts | BEHRINGWERKE AG (DE) | 1996-07-02 | — | — | US | disclosed |