Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | LSS | P48449 | 2/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 7/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9020953 | 0.88 | ALDH1A1 (0.54) | ALDH1A1CYP19A1POLBLMNAKMT2A | |
| SCHEMBL9020919 | 0.84 | ALDH1A1 (0.50) | ALDH1A1CYP19A1POLBLMNAKMT2A | |
| SCHEMBL7876913 | 0.82 | ALDH1A1 (0.53) | ALDH1A1LSSCYP19A1POLBL3MBTL1 | |
| SCHEMBL9020770 | 0.76 | LMNA (0.50) | CYP19A1POLBLMNATBXAS1 | |
| SCHEMBL9020694 | 0.73 | QPCT (0.50) | ALDH1A1CYP19A1POLBLMNASMN1; SMN2 | |
| SCHEMBL9129290 | 0.71 | TBXAS1 (0.63) | ALDH1A1LSSCYP19A1POLBL3MBTL1 | |
| SCHEMBL11475222 | 0.71 | CYP19A1 (0.68) | CYP19A1L3MBTL1TBXAS1CYP11B1CYP11B2 | |
| SCHEMBL9021127 | 0.71 | LMNA (0.52) | POLBLMNAHTTSMN1; SMN2KMT2A | |
| SCHEMBL16351172 | 0.70 | ALDH1A1 (1.00) | ALDH1A1CYP19A1POLBL3MBTL1LMNA | |
| SCHEMBL7873784 | 0.69 | ALDH1A1 (0.55) | ALDH1A1CYP19A1POLBLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705251-A1 | IMIDAZOLE DERIVATIVES AS THERAPEUTIC AGENTS | Knoll AG (DE) | 1996-04-10 | — | — | EP | disclosed |