SCHEMBL9020973

SCHEMBL9020973

Cc1cccc(Oc2ccc(OCCCn3cccn3)cc2)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.52
TSHR P16473 2/20 0.48
CYP1A2 P05177 1/20 0.47
CYP3A4 P08684 1/20 0.47
CYP2D6 P10635 1/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
L3MBTL1 Q9Y468 2/20 0.46
KDM4E B2RXH2 2/20 0.46
ALDH1A1 P00352 3/20 0.44
DRD2 P14416 2/20 0.44
DRD4 P21917 2/20 0.44
DRD3 P35462 1/20 0.44
LTA4H P09960 2/20 0.43
TDP1 Q9NUW8 1/20 0.41
CACNA1B Q00975 1/20 0.41
QPCT Q16769 1/20 0.41
RAB9A P51151 1/20 0.41
MAPT P10636 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL27749715 0.88 KMT2A (0.59) KMT2ATSHRCYP1A2CYP3A4CYP2D6
SCHEMBL9021032 0.85 LTA4H (0.56) KMT2ATSHRSMN1; SMN2KDM4EALDH1A1
SCHEMBL11866 0.84 KMT2A (0.56) KMT2ATSHRCYP1A2CYP3A4CYP2D6
SCHEMBL9723089 0.80 ALDH1A1 (0.42) KMT2ATSHRSMN1; SMN2KDM4EALDH1A1
SCHEMBL9020977 0.79 MEN1 (0.44) KMT2ACYP1A2CYP2D6CYP2C9CYP2C19
SCHEMBL14136068 0.76 ALDH1A1 (0.57) KMT2ATSHRSMN1; SMN2L3MBTL1KDM4E
SCHEMBL9459912 0.76 TSHR (0.46) KMT2ATSHRKDM4EALDH1A1
SCHEMBL10786354 0.76 ALDH1A1 (0.49) KMT2ACYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL16417745 0.75 MEN1 (0.59) KMT2ASMN1; SMN2KDM4EALDH1A1TDP1
SCHEMBL687762 0.74 TBXAS1 (0.58) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0376598-B1 Pyrazole compounds, and their production and use SUMITOMO CHEMICAL CO (JP) 1996-02-21 EP disclosed