Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.43 |
| ▸ | QPCT | Q16769 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | DRD4 | P21917 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9021032 | 0.84 | LTA4H (0.56) | MEN1LMNAKMT2AALDH1A1CACNA1B | |
| SCHEMBL15061998 | 0.79 | IDO1 (0.55) | MEN1LMNAKMT2AMAPK1ALDH1A1 | |
| SCHEMBL9020973 | 0.79 | KMT2A (0.52) | KMT2AALDH1A1CACNA1BQPCTDRD2 | |
| SCHEMBL10786354 | 0.76 | ALDH1A1 (0.49) | MEN1LMNAKMT2AALDH1A1DRD2 | |
| SCHEMBL16417745 | 0.76 | MEN1 (0.59) | MEN1LMNAKMT2AALDH1A1THRB | |
| SCHEMBL9723089 | 0.75 | ALDH1A1 (0.42) | MEN1LMNAKMT2AALDH1A1CACNA1B | |
| SCHEMBL7626009 | 0.75 | MAPT (0.54) | MEN1LMNAKMT2AALDH1A1THRB | |
| SCHEMBL9020798 | 0.73 | DRD2 (0.50) | MEN1KMT2AALDH1A1CACNA1BDRD2 | |
| SCHEMBL15918573 | 0.72 | CYP19A1 (0.59) | MEN1LMNAKMT2AMAPK1ALDH1A1 | |
| SCHEMBL9459912 | 0.72 | TSHR (0.46) | MEN1LMNAKMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0376598-B1 | Pyrazole compounds, and their production and use | SUMITOMO CHEMICAL CO (JP) | 1996-02-21 | — | — | EP | disclosed |