Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.53 |
| ▸ | CXCR6 | O00574 | 8/20 | 0.53 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.51 |
| ▸ | DRD4 | P21917 | 2/20 | 0.49 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9021658 | 0.96 | HTR4 (0.52) | DRD2CXCR6CXCR4DRD4HTR4 | |
| SCHEMBL9021584 | 0.93 | OPRK1 (0.49) | DRD2CXCR6CXCR4DRD4 | |
| Maleic Acid SCHEMBL9021974 | 0.92 | HTR4 (0.47) | DRD2CXCR6CXCR4DRD4HTR4 | |
| SCHEMBL9022191 | 0.92 | DRD2 (0.54) | DRD2CXCR6CXCR4DRD4HTR4 | |
| SCHEMBL9021504 | 0.90 | DRD2 (0.51) | DRD2CXCR6CXCR4DRD4HTR4 | |
| SCHEMBL9021809 | 0.89 | DRD2 (0.50) | DRD2CXCR6CXCR4DRD4HTR4 | |
| SCHEMBL9021510 | 0.87 | DRD2 (0.70) | DRD2HTR4 | |
| SCHEMBL9021762 | 0.86 | HTR4 (0.51) | DRD2DRD4HTR4 | |
| Fumaric Acid SCHEMBL9076217 | 0.85 | DRD2 (0.48) | DRD2CXCR6CXCR4DRD4HTR4 | |
| SCHEMBL9021444 | 0.84 | HTR4 (0.66) | DRD2DRD4HTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640601-B1 | BENZAMIDE DERIVATIVE | HOKURIKU PHARMACEUTICAL (JP) | 1996-12-04 | — | — | EP | disclosed |
| US-5500422-A | FOR TREATING GASTROINTESTINAL DISEASES | HOKURIKU SEIYAKU CO. LTD. (JP) | 1996-03-19 | — | — | US | disclosed |
| US-5395832-A | Gastrointestinal disorders | HOKURIKU SEIYAKU CO., LTD. (JP) | 1995-03-07 | — | — | US | disclosed |
| EP-0640601-A1 | BENZAMIDE DERIVATIVE | HOKURIKU SEIYAKU CO., LTD. (JP) | 1995-03-01 | — | — | EP | disclosed |