SCHEMBL9022737

SCHEMBL9022737

C1=CC2CC1CC2c1ccccn1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.37
MAPT P10636 2/20 0.37
NPC1 O15118 2/20 0.37
RAB9A P51151 2/20 0.37
KMT2A Q03164 1/20 0.37
KDM4E B2RXH2 6/20 0.35
LMNA P02545 3/20 0.35
CCR1 P32246 2/20 0.35
CCR5 P51681 2/20 0.35
CCR8 P51685 2/20 0.35
CYP1A2 P05177 1/20 0.35
POLB P06746 1/20 0.35
METAP1 P53582 1/20 0.35
BLM P54132 1/20 0.35
HIF1A Q16665 1/20 0.35
DOHH Q9BU89 1/20 0.35
P4HTM Q9NXG6 1/20 0.35
DDB1 Q16531 1/20 0.34
CRBN Q96SW2 1/20 0.34
DPP4 P27487 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27921494 0.71 ALDH1A1 (0.42) ALDH1A1MAPTNPC1RAB9AKMT2A
SCHEMBL369985 0.71 ALDH1A1 (0.42) ALDH1A1MAPTNPC1RAB9AKMT2A
SCHEMBL28168522 0.71 NPC1 (0.47) ALDH1A1MAPTNPC1RAB9AKMT2A
SCHEMBL24868506 0.71 ALDH1A1 (0.42) ALDH1A1MAPTNPC1RAB9AKMT2A
SCHEMBL12143649 0.71 ALDH1A1 (0.42) ALDH1A1MAPTNPC1RAB9AKMT2A
SCHEMBL24867570 0.71 ALDH1A1 (0.42) ALDH1A1MAPTNPC1RAB9AKMT2A
SCHEMBL899802 0.71 NPC1 (0.47) ALDH1A1MAPTNPC1RAB9AKMT2A
SCHEMBL19013047 0.71 ALDH1A1 (0.42) ALDH1A1MAPTNPC1RAB9AKMT2A
SCHEMBL109753 0.71 MAOB (0.46) KDM4ELMNACYP1A2BLMTSHR
SCHEMBL18587142 0.69 HTR2C (0.37) ALDH1A1KMT2AKDM4ELMNACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0251033-B1 METATHESIS POLYMERIZATION OF CYCLOOLEFINS HERCULES INCORPORATED (US) 1993-03-03 EP claimed
US-4900799-A Metathesis polymerization of cycloolefins TEIJIN LIMITED (JP) 1990-02-13 US claimed
EP-0251033-A2 Metathesis polymerization of cycloolefins HERCULES INCORPORATED (US) 1988-01-07 EP claimed
EP-0451858-B1 Molded article of norbornene-based polymer NIPPON ZEON CO (JP) 1996-10-09 EP disclosed
US-5302656-A Heat resistance, crack resistance NIPPON ZEON CO., LTD. (JP) 1994-04-12 US disclosed
EP-0251033-B1 METATHESIS POLYMERIZATION OF CYCLOOLEFINS HERCULES INCORPORATED (US) 1993-03-03 EP disclosed
US-5063096-A Norbornene polymer substrates; containing metallic oxide or fluoride NIPPON ZEON CO., LTD. (JP) 1991-11-05 US disclosed
EP-0451858-A2 Molded article of norbornene-based polymer NIPPON ZEON CO., LTD. (JP) 1991-10-16 EP disclosed
US-4900799-A Metathesis polymerization of cycloolefins TEIJIN LIMITED (JP) 1990-02-13 US disclosed
EP-0251033-A2 Metathesis polymerization of cycloolefins HERCULES INCORPORATED (US) 1988-01-07 EP disclosed
US-4080491-A CATALYST CONTAINS ORGANOMETALLIC COMPOUND AND THE REACTION PRODUCT OF TUNGSTEN OR MOLYBDENUM OXIDE AND A PHOSPHOROUS HALIDE OR OXYHALIDE SHOWA DENKO K.K. (JA) 1978-03-21 US disclosed
US-4059561-A AND A HALOGEN COMPOUND SHOWA DENKO KABUSHIKI KAISHA (JA) 1977-11-22 US disclosed
US-3991139-A NORBORNENE DERIVATIVES, PHENOLS, ESTER THIOETHERS SHOWA DENKO KABUSHIKI KAISHA (JA) 1976-11-09 US disclosed