Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL774999 | 0.83 | ALDH1A1 (0.35) | ALDH1A1TSHRLMNA | |
| SCHEMBL9023021 | 0.77 | ALDH1A1 (0.31) | ALDH1A1TSHR | |
| SCHEMBL8768693 | 0.76 | — | — | |
| SCHEMBL138696 | 0.75 | L3MBTL1 (0.32) | ALDH1A1TSHRLMNA | |
| SCHEMBL13976468 | 0.74 | LMNA (0.36) | ALDH1A1LMNA | |
| SCHEMBL4713920 | 0.71 | — | — | |
| SCHEMBL98777 | 0.70 | TSHR (0.40) | TSHR | |
| SCHEMBL332472 | 0.68 | — | — | |
| SCHEMBL27570533 | 0.68 | LMNA (0.40) | ALDH1A1LMNA | |
| SCHEMBL243552 | 0.68 | LMNA (0.40) | ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0548250-B1 | SUBSTITUTED BICYCLIC ARYL COMPOUNDS EXHIBITING SELECTIVE LEUKOTRIENE B4 ANTAGONIST ACTIVITY | RHONE POULENC RORER INT (US) | 1996-03-27 | — | — | EP | disclosed |
| US-5468898-A | Substituted naphthylene compounds exhibiting selective leukotriene B4 antagonist activity | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1995-11-21 | — | — | US | disclosed |