Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | RGS12 | O14924 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9023793 | 0.83 | ALDH1A1 (0.41) | MAPTALDH1A1KDM4ELMNAHSD17B10 | |
| SCHEMBL9025389 | 0.81 | KDM1A (0.41) | MAPTALDH1A1KDM4ELMNAHSD17B10 | |
| SCHEMBL8548431 | 0.80 | MEN1 (0.38) | MAPTALDH1A1KDM4ELMNAHSD17B10 | |
| SCHEMBL9025371 | 0.79 | CYP1A2 (0.44) | MAPTALDH1A1KDM4ELMNAHSD17B10 | |
| SCHEMBL9025257 | 0.77 | KDM4E (0.40) | MAPTALDH1A1KDM4ELMNAHSD17B10 | |
| SCHEMBL9024798 | 0.75 | NQO2 (0.56) | ALDH1A1KDM4ELMNAMEN1KMT2A | |
| SCHEMBL9024575 | 0.74 | NQO2 (0.36) | HPGDRECQLGLAAPEX1SYK | |
| SCHEMBL9739130 | 0.74 | NQO2 (0.46) | ALDH1A1KDM4EHSD17B10PARP1HPGD | |
| SCHEMBL9023664 | 0.74 | KDM4E (0.45) | MAPTKDM4ELMNAHTTNQO1 | |
| SCHEMBL9024667 | 0.72 | NQO1 (0.39) | ALDH1A1KDM4ELMNATSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0347749-B1 | Pyrazoloacridone derivatives with anti-tumoral activity | KYOWA HAKKO KOGYO KK (JP) | 1996-04-24 | — | — | EP | disclosed |
| US-5079358-A | Humans; leukemia | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-01-07 | — | — | US | disclosed |
| EP-0347749-A2 | Pyrazoloacridone derivatives with anti-tumoral activity | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1989-12-27 | — | — | EP | disclosed |