Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 5/20 | 0.39 |
| ▸ | NQO2 | P16083 | 5/20 | 0.39 |
| ▸ | TERT | O14746 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | SRC | P12931 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9024575 | 0.88 | NQO2 (0.36) | NQO1NQO2 | |
| SCHEMBL9739130 | 0.84 | NQO2 (0.46) | NQO1NQO2KDM4EALDH1A1 | |
| SCHEMBL2725699 | 0.82 | NQO1 (0.39) | NQO1NQO2KDM4EALOX15TSHR | |
| SCHEMBL9023717 | 0.81 | L3MBTL1 (0.43) | KDM4EALOX15TSHRLMNAMEN1 | |
| SCHEMBL9023847 | 0.79 | G6PD (0.39) | NQO1NQO2 | |
| SCHEMBL9024703 | 0.76 | NQO2 (0.48) | NQO1NQO2 | |
| SCHEMBL9024920 | 0.75 | NQO2 (0.47) | NQO1NQO2KMT2A | |
| SCHEMBL9024106 | 0.75 | NQO2 (0.47) | NQO1NQO2 | |
| SCHEMBL9023722 | 0.74 | TOP2A (0.38) | NQO1NQO2 | |
| SCHEMBL9024299 | 0.74 | NQO2 (0.49) | NQO1NQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0347749-B1 | Pyrazoloacridone derivatives with anti-tumoral activity | KYOWA HAKKO KOGYO KK (JP) | 1996-04-24 | — | — | EP | disclosed |