Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL932804 | 0.73 | HTR1A (0.37) | POLB | |
| SCHEMBL5755407 | 0.66 | THRB (0.38) | — | |
| SCHEMBL5558305 | 0.65 | CYP17A1 (0.34) | — | |
| SCHEMBL272489 | 0.63 | BRS3 (0.32) | — | |
| SCHEMBL3951665 | 0.63 | HRH3 (0.41) | — | |
| SCHEMBL10785918 | 0.63 | KCNA3 (0.43) | — | |
| SCHEMBL5656590 | 0.62 | HRH3 (0.43) | — | |
| SCHEMBL6743169 | 0.61 | TSHR (0.51) | POLB | |
| SCHEMBL348921 | 0.61 | ALDH1A1 (0.60) | — | |
| SCHEMBL11088046 | 0.60 | ESR1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0398179-B1 | Rhodanine derivatives and pharmaceutical compositions | NISSHIN FLOUR MILLING CO (JP) | 1996-01-17 | — | — | EP | disclosed |
| US-5116855-A | Aldose reductase inhibitors; antidiabetic agents | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1992-05-26 | — | — | US | disclosed |
| EP-0398179-A1 | Rhodanine derivatives and pharmaceutical compositions | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1990-11-22 | — | — | EP | disclosed |