Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 7/20 | 0.34 |
| ▸ | NQO1 | P15559 | 6/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | G6PD | P11413 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.31 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9023550 | 0.86 | G6PD (0.46) | NQO2NQO1ALDH1A1G6PDPARP1 | |
| SCHEMBL9023982 | 0.83 | MAPT (0.36) | G6PDMAPTHTT | |
| SCHEMBL9024240 | 0.83 | KDM1A (0.38) | NQO2NQO1PARP1P2RX4 | |
| SCHEMBL9025088 | 0.82 | ALDH1A1 (0.40) | NQO2NQO1ALDH1A1PARP1CYP1A2 | |
| SCHEMBL9023793 | 0.81 | ALDH1A1 (0.41) | NQO2NQO1ALDH1A1PARP1CYP1A2 | |
| SCHEMBL9024132 | 0.80 | ALDH1A1 (0.33) | ALDH1A1PARP1MAPTHTTGLA | |
| SCHEMBL9737446 | 0.77 | NQO1 (0.33) | NQO2NQO1 | |
| SCHEMBL9024950 | 0.77 | AR (0.40) | NQO2NQO1PARP1MAPTHTT | |
| SCHEMBL9024099 | 0.75 | NQO1 (0.32) | NQO2NQO1 | |
| SCHEMBL9024559 | 0.73 | MAPT (0.39) | G6PDMAPTHTTCYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0347749-B1 | Pyrazoloacridone derivatives with anti-tumoral activity | KYOWA HAKKO KOGYO KK (JP) | 1996-04-24 | — | — | EP | disclosed |
| US-5079358-A | Humans; leukemia | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-01-07 | — | — | US | disclosed |
| EP-0347749-A2 | Pyrazoloacridone derivatives with anti-tumoral activity | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1989-12-27 | — | — | EP | disclosed |