Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | RAD52 | P43351 | 4/20 | 0.41 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9024060 | 0.85 | KDM4E (0.51) | ALDH1A1HPGDKDM4EHSD17B10KMT2A | |
| SCHEMBL9024540 | 0.80 | KMT2A (0.45) | ALDH1A1HPGDKDM4EHSD17B10KMT2A | |
| SCHEMBL9023686 | 0.69 | HTT (0.34) | ALDH1A1HPGDKDM4EKMT2AMEN1 | |
| SCHEMBL9032596 | 0.69 | NQO2 (0.46) | RAD52SMARCA2NQO1NQO2 | |
| SCHEMBL9024672 | 0.68 | ALDH1A1 (0.44) | ALDH1A1HPGDKDM4ERXFP1 | |
| SCHEMBL9024039 | 0.68 | NQO2 (0.43) | RAD52SMARCA2NQO1NQO2 | |
| SCHEMBL9023748 | 0.66 | NQO2 (0.40) | NQO1NQO2 | |
| SCHEMBL9024980 | 0.66 | NQO2 (0.43) | RAD52NQO1NQO2 | |
| SCHEMBL3362006 | 0.65 | ALDH1A1 (0.62) | ALDH1A1HPGDKDM4EKMT2AMEN1 | |
| SCHEMBL9738372 | 0.63 | NQO2 (0.46) | ALDH1A1HPGDKDM4EHSD17B10NQO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0347749-B1 | Pyrazoloacridone derivatives with anti-tumoral activity | KYOWA HAKKO KOGYO KK (JP) | 1996-04-24 | — | — | EP | disclosed |
| US-5079358-A | Humans; leukemia | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-01-07 | — | — | US | disclosed |