Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 6/20 | 0.37 |
| ▸ | CCKBR | P32239 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9027409 | 0.81 | MAPT (0.42) | GPR84MAPTTDP1MEN1KMT2A | |
| SCHEMBL9026979 | 0.78 | GPR84 (0.41) | GPR84CYP3A4MAPTTDP1MEN1 | |
| SCHEMBL9027306 | 0.78 | TACR1 (0.41) | TP53MAPTTSHR | |
| SCHEMBL9026402 | 0.76 | GPR84 (0.45) | GPR84MAPTMTNR1BMTNR1AMEN1 | |
| SCHEMBL9027482 | 0.76 | PCSK9 (0.38) | GPR84MAPTMEN1KMT2A | |
| SCHEMBL9025363 | 0.76 | LTA4H (0.46) | GPR84MAPTMEN1KMT2A | |
| SCHEMBL9026147 | 0.75 | KMT2A (0.40) | GPR84CYP3A4MAPTTDP1MEN1 | |
| SCHEMBL9027221 | 0.74 | PDE10A (0.36) | MAPTMEN1KMT2A | |
| SCHEMBL9026518 | 0.73 | GPR84 (0.44) | GPR84NR4A2MTNR1BMTNR1A | |
| SCHEMBL9026185 | 0.73 | GPR84 (0.41) | GPR84CYP3A4MAPTTDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0411150-B1 | INDOLE DERIVATIVES, PREPARATION THEREOF, AND DRUG FOR PREVENTING AND TREATING NEPHRITIS CONTAINING SAME | OTSUKA PHARMA CO LTD (JP) | 1996-11-27 | — | — | EP | disclosed |