Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 2/20 | 0.37 |
| ▸ | MMP2 | P08253 | 2/20 | 0.37 |
| ▸ | MMP3 | P08254 | 2/20 | 0.37 |
| ▸ | MMP7 | P09237 | 2/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9027006 | 0.82 | ALDH1A1 (0.38) | HPGDMMP2NR4A2L3MBTL1LMNA | |
| SCHEMBL9026948 | 0.82 | LMNA (0.39) | SMN1; SMN2HPGDNPC1RAB9AMMP2 | |
| SCHEMBL27257352 | 0.81 | SMN1; SMN2 (0.42) | SMN1; SMN2TP53NPSR1MAPTHPGD | |
| SCHEMBL9026147 | 0.80 | KMT2A (0.40) | MAPTMEN1KMT2AGPR84MMP2 | |
| SCHEMBL27258448 | 0.78 | LMNA (0.39) | SMN1; SMN2MAPTHPGDMEN1KMT2A | |
| SCHEMBL9026029 | 0.77 | ALDH1A1 (0.40) | NPSR1MAPTHPGDL3MBTL1LMNA | |
| SCHEMBL9027351 | 0.75 | SMN1; SMN2 (0.44) | SMN1; SMN2TP53NPSR1MAPTHPGD | |
| SCHEMBL9026638 | 0.74 | KMT2A (0.39) | MAPTMEN1KMT2AGPR84MMP2 | |
| SCHEMBL9026324 | 0.74 | JAK2 (0.36) | SMN1; SMN2MAPTMEN1KMT2ANPC1 | |
| SCHEMBL9025363 | 0.73 | LTA4H (0.46) | MAPTMEN1KMT2AGPR84MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0411150-B1 | INDOLE DERIVATIVES, PREPARATION THEREOF, AND DRUG FOR PREVENTING AND TREATING NEPHRITIS CONTAINING SAME | OTSUKA PHARMA CO LTD (JP) | 1996-11-27 | — | — | EP | disclosed |
| US-5238938-A | Nephrosis | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-08-24 | — | — | US | disclosed |
| EP-0411150-A1 | INDOLE DERIVATIVES, PREPARATION THEREOF, AND DRUG FOR PREVENTING AND TREATING NEPHRITIS CONTAINING SAME | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-02-06 | — | — | EP | disclosed |