Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 4/20 | 0.34 |
| ▸ | HTR1A | P08908 | 2/20 | 0.34 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9026642 | 0.89 | KMT2A (0.39) | SLC9A1HPGDTSHRMEN1KMT2A | |
| SCHEMBL9026539 | 0.87 | SLC9A1 (0.37) | SLC9A1SLC6A4HPGDTSHRMEN1 | |
| SCHEMBL9025868 | 0.83 | HPGD (0.38) | POLBHPGDTSHRMEN1KMT2A | |
| SCHEMBL9025850 | 0.81 | RAB9A (0.37) | SLC9A1HPGDTSHRMEN1KMT2A | |
| SCHEMBL9025574 | 0.80 | CCR2 (0.42) | HPGDTSHRMEN1KMT2ANPC1 | |
| SCHEMBL9026261 | 0.79 | TSHR (0.39) | SLC9A1HPGDTSHRMEN1KMT2A | |
| SCHEMBL9026398 | 0.79 | KDM4E (0.39) | SLC9A1HPGDTSHRMEN1KMT2A | |
| SCHEMBL9026425 | 0.79 | TSHR (0.35) | POLBSLC9A1HPGDTSHRMEN1 | |
| SCHEMBL9026585 | 0.77 | MAPT (0.36) | POLBSLC9A1HPGDMEN1KMT2A | |
| SCHEMBL9026419 | 0.77 | HPGD (0.48) | POLBHPGDTSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711290-A1 | METHYLGUANIDINE DERIVATIVES, METHODS FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAID DERIVATIVES | SANOFI (FR) | 1996-05-15 | — | — | EP | disclosed |
| WO-1995004052-A1 | METHYLGUANIDINE DERIVATIVES, METHODS FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAID DERIVATIVES | SANOFI (FR) | 1995-02-09 | — | — | WO | disclosed |