Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | MAP2 | P11137 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9026642 | 0.89 | KMT2A (0.39) | SLC9A1MAPTSMN1; SMN2HPGDLMNA | |
| SCHEMBL9026431 | 0.87 | POLB (0.37) | SLC9A1MAPTTP53HPGDLMNA | |
| SCHEMBL9025868 | 0.84 | HPGD (0.38) | MAPTSMN1; SMN2TP53HPGDLMNA | |
| SCHEMBL9025850 | 0.82 | RAB9A (0.37) | SLC9A1MAPTSMN1; SMN2TP53HPGD | |
| SCHEMBL9025574 | 0.81 | CCR2 (0.42) | MAPTSMN1; SMN2TP53HPGDLMNA | |
| SCHEMBL9026261 | 0.80 | TSHR (0.39) | SLC9A1MAPTSMN1; SMN2TP53HPGD | |
| SCHEMBL9026398 | 0.80 | KDM4E (0.39) | SLC9A1MAPTSMN1; SMN2TP53HPGD | |
| SCHEMBL9026534 | 0.78 | SLC9A1 (0.35) | SLC9A1MAPTIRAK4KMT2AMEN1 | |
| SCHEMBL9025661 | 0.78 | TSHR (0.46) | MAPTSMN1; SMN2TP53HPGDTSHR | |
| SCHEMBL9026419 | 0.78 | HPGD (0.48) | MAPTSMN1; SMN2HPGDLMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711290-A1 | METHYLGUANIDINE DERIVATIVES, METHODS FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAID DERIVATIVES | SANOFI (FR) | 1996-05-15 | — | — | EP | disclosed |
| WO-1995004052-A1 | METHYLGUANIDINE DERIVATIVES, METHODS FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAID DERIVATIVES | SANOFI (FR) | 1995-02-09 | — | — | WO | disclosed |