Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 6/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9025850 | 0.92 | RAB9A (0.37) | KMT2AMEN1RAB9AHPGDKDM4E | |
| SCHEMBL9026261 | 0.90 | TSHR (0.39) | KMT2AMEN1RAB9AHPGDKDM4E | |
| SCHEMBL9026398 | 0.90 | KDM4E (0.39) | KMT2AMEN1RAB9AHPGDKDM4E | |
| SCHEMBL9026539 | 0.89 | SLC9A1 (0.37) | KMT2AMEN1RAB9AHPGDKDM4E | |
| SCHEMBL9026431 | 0.89 | POLB (0.37) | KMT2AMEN1RAB9AHPGDTSHR | |
| SCHEMBL9026419 | 0.88 | HPGD (0.48) | KMT2AMEN1RAB9AHPGDKDM4E | |
| SCHEMBL9025661 | 0.88 | TSHR (0.46) | KMT2AMEN1RAB9AHPGDKDM4E | |
| SCHEMBL9026139 | 0.87 | RAB9A (0.39) | KMT2AMEN1RAB9AHPGDKDM4E | |
| SCHEMBL9024890 | 0.87 | RAB9A (0.39) | KMT2AMEN1RAB9AHPGDKDM4E | |
| SCHEMBL9026454 | 0.86 | PTGS2 (0.39) | KMT2AMEN1RAB9AHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711290-A1 | METHYLGUANIDINE DERIVATIVES, METHODS FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAID DERIVATIVES | SANOFI (FR) | 1996-05-15 | — | — | EP | disclosed |
| WO-1995004052-A1 | METHYLGUANIDINE DERIVATIVES, METHODS FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAID DERIVATIVES | SANOFI (FR) | 1995-02-09 | — | — | WO | disclosed |