Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 2/20 | 0.36 |
| ▸ | LDHA | P00338 | 2/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.33 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6603974 | 0.91 | ALDH1A1 (0.38) | ALDH1A1DAOLDHAEGFRGAA | |
| SCHEMBL6608872 | 0.88 | LDHA (0.41) | DAOLDHAEGFRGAAL3MBTL1 | |
| SCHEMBL9027786 | 0.87 | LDHA (0.37) | DAOLDHAGPR84EGFRUTS2R | |
| SCHEMBL6609678 | 0.82 | LDHA (0.40) | LDHAEGFRGAAL3MBTL1OPRM1 | |
| SCHEMBL9026058 | 0.81 | LDHA (0.43) | DAOLDHAGPR84 | |
| SCHEMBL6603192 | 0.81 | LDHA (0.39) | LDHAEGFRGAAL3MBTL1LMNA | |
| SCHEMBL8658523 | 0.80 | TAAR1 (0.41) | ALDH1A1LDHAGAAL3MBTL1LMNA | |
| SCHEMBL6606198 | 0.80 | LDHA (0.39) | LDHAEGFRGAAL3MBTL1LMNA | |
| SCHEMBL6608780 | 0.79 | NPC1 (0.36) | ALDH1A1DAOLDHAGPR84L3MBTL1 | |
| SCHEMBL9195240 | 0.78 | LDHA (0.38) | LDHAEGFRGAAL3MBTL1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0729463-A1 | 5,6-DIHYDROPYRONE DERIVATIVES AS PROTEASE INHIBITORS AND ANTIVIRAL AGENTS | PARKE DAVIS & COMPANY (US) | 1996-09-04 | — | — | EP | disclosed |