Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 7/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 6/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8632709 | 0.87 | KDM4E (0.44) | ALDH1A1SMN1; SMN2MAPTMAPK1KDM4E | |
| SCHEMBL9026125 | 0.87 | BRD4 (0.36) | BRD4CREBBP | |
| SCHEMBL8633722 | 0.75 | BRD4 (0.41) | ALDH1A1SMN1; SMN2MAPTMAPK1BRD4 | |
| SCHEMBL8634032 | 0.73 | IMPDH2 (0.39) | ALDH1A1SMN1; SMN2MAPTMAPK1BRD4 | |
| SCHEMBL8636185 | 0.72 | BRD4 (0.43) | ALDH1A1SMN1; SMN2MAPTMAPK1KDM4E | |
| SCHEMBL8632301 | 0.69 | GAA (0.44) | ALDH1A1SMN1; SMN2MAPTMAPK1BRD4 | |
| SCHEMBL8981644 | 0.69 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2MAPTMAPK1KDM4E | |
| SCHEMBL8634779 | 0.67 | KMT2A (0.38) | ALDH1A1SMN1; SMN2MAPTMAPK1KDM4E | |
| SCHEMBL8629576 | 0.67 | BRD4 (0.44) | ALDH1A1SMN1; SMN2MAPTMAPK1BRD4 | |
| SCHEMBL8634802 | 0.67 | ALDH1A1 (0.38) | ALDH1A1SMN1; SMN2MAPTMAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0707574-A1 | NOVEL (1-PHENYL-1-HETEROCYCLYL)METHANOL AND (1-PHENYL-1-HETEROCYCLYL)METHYLAMINE DERIVATIVES | Astra Aktiebolag (SE) | 1996-04-24 | — | — | EP | disclosed |
| WO-1995001968-A1 | NOVEL (1-PHENYL-1-HETEROCYCLYL)METHANOL AND (1-PHENYL-1-HETEROCYCLYL)METHYLAMINE DERIVATIVES | ASTRA AKTIEBOLAG (SE) | 1995-01-19 | — | — | WO | disclosed |