Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 1/20 | 0.39 |
| ▸ | KDM5A | P29375 | 1/20 | 0.37 |
| ▸ | ACP3 | P15309 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 5/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9026606 | 0.88 | ALOX5 (0.35) | IMPDH2KDM5AEPHX1ALDH1A1MAPT | |
| SCHEMBL8632709 | 0.83 | KDM4E (0.44) | ALDH1A1MAPTMAPK1SMN1; SMN2BRD4 | |
| SCHEMBL8633722 | 0.80 | BRD4 (0.41) | ACHEALDH1A1MAPTMAPK1SMN1; SMN2 | |
| SCHEMBL822105 | 0.75 | ACHE (0.52) | KDM5AACP3ACHEEPHX1IDO1 | |
| SCHEMBL8636185 | 0.74 | BRD4 (0.43) | ALDH1A1MAPTMAPK1SMN1; SMN2BRD4 | |
| SCHEMBL9026465 | 0.73 | ALDH1A1 (0.39) | ALDH1A1MAPTMAPK1SMN1; SMN2BRD4 | |
| SCHEMBL8632301 | 0.71 | GAA (0.44) | ACP3IDO1TDO2ALDH1A1MAPT | |
| SCHEMBL18292866 | 0.70 | IDO1 (0.40) | KDM5AACP3ACHEEPHX1IDO1 | |
| SCHEMBL477409 | 0.70 | ACP3 (0.55) | ACP3ACHEEPHX1SMN1; SMN2OPRM1 | |
| SCHEMBL30502803 | 0.70 | ACP3 (0.55) | ACP3ACHEEPHX1SMN1; SMN2OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5712299-A | TREATMENT OF NEURODEGENERATIVE DISORDERS | ASTRA AKTIEBOLAG (SE) | 1998-01-27 | — | — | US | disclosed |