Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.30 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.30 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.30 |
| ▸ | FNTA | P49354 | 1/20 | 0.30 |
| ▸ | FNTB | P49356 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9027880 | 0.90 | FNTA (0.33) | SIGMAR1GRM2PDE4APRMT5WDR77 | |
| SCHEMBL9027888 | 0.90 | FNTA (0.33) | SIGMAR1GRM2PDE4APRMT5WDR77 | |
| SCHEMBL9027157 | 0.87 | MMP2 (0.33) | SIGMAR1GRM2 | |
| SCHEMBL9027149 | 0.87 | MMP2 (0.33) | SIGMAR1GRM2 | |
| SCHEMBL9027929 | 0.85 | POLB (0.36) | SIGMAR1POLB | |
| SCHEMBL9027003 | 0.84 | OPRK1 (0.33) | SIGMAR1POLB | |
| SCHEMBL9026999 | 0.84 | OPRK1 (0.33) | SIGMAR1POLB | |
| SCHEMBL9027017 | 0.83 | SIGMAR1 (0.30) | SIGMAR1 | |
| SCHEMBL9027013 | 0.83 | SIGMAR1 (0.30) | SIGMAR1 | |
| SCHEMBL9026631 | 0.83 | ECE1 (0.37) | PDCD1CD274PRMT5WDR77FNTA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0722447-A1 | 3-PYRROLIDINYLTHIO-CARBAPENEM DERIVATIVES AND THEIR ANTIMICROBAL ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-07-24 | — | — | EP | disclosed |
| WO-1995010520-A1 | 3-PYRROLIDINYLTHIO-CARBAPENEM DERIVATIVES AND THEIR ANTIMICROBAL ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-20 | — | — | WO | disclosed |