Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.32 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 8/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CSF1R | P07333 | 1/20 | 0.31 |
| ▸ | MMP12 | P39900 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9026999 | 1.00 | OPRK1 (0.33) | OPRK1KCNH2SIGMAR1CYP4F2CYP4A11 | |
| SCHEMBL9027356 | 0.89 | OPRK1 (0.33) | OPRK1KCNH2SIGMAR1CYP4F2CYP4A11 | |
| SCHEMBL9027374 | 0.89 | OPRK1 (0.33) | OPRK1KCNH2SIGMAR1CYP4F2CYP4A11 | |
| SCHEMBL9027929 | 0.87 | POLB (0.36) | SIGMAR1POLB | |
| SCHEMBL9026520 | 0.86 | MMP2 (0.35) | OPRK1KCNH2SIGMAR1CYP4F2CYP4A11 | |
| SCHEMBL9026560 | 0.84 | PDCD1 (0.34) | SIGMAR1POLB | |
| SCHEMBL9221010 | 0.84 | SNCA (0.38) | SIGMAR1POLB | |
| SCHEMBL8832922 | 0.84 | SNCA (0.38) | SIGMAR1POLB | |
| SCHEMBL9027579 | 0.83 | POLB (0.34) | SIGMAR1POLB | |
| SCHEMBL9027582 | 0.83 | POLB (0.34) | SIGMAR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0722447-A1 | 3-PYRROLIDINYLTHIO-CARBAPENEM DERIVATIVES AND THEIR ANTIMICROBAL ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-07-24 | — | — | EP | disclosed |
| WO-1995010520-A1 | 3-PYRROLIDINYLTHIO-CARBAPENEM DERIVATIVES AND THEIR ANTIMICROBAL ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-20 | — | — | WO | disclosed |