Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 3/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | SLC6A15 | Q9H2J7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9026999 | 0.87 | OPRK1 (0.33) | POLBSIGMAR1 | |
| SCHEMBL9027003 | 0.87 | OPRK1 (0.33) | POLBSIGMAR1 | |
| SCHEMBL9027754 | 0.87 | MMP2 (0.34) | SIGMAR1CYP19A1 | |
| SCHEMBL9027764 | 0.87 | MMP2 (0.34) | SIGMAR1CYP19A1 | |
| SCHEMBL9027579 | 0.86 | POLB (0.34) | POLBSIGMAR1CYP19A1FAAH | |
| SCHEMBL9027582 | 0.86 | POLB (0.34) | POLBSIGMAR1CYP19A1FAAH | |
| SCHEMBL9026560 | 0.85 | PDCD1 (0.34) | POLBSIGMAR1 | |
| SCHEMBL9221010 | 0.85 | SNCA (0.38) | POLBSIGMAR1CYP19A1FAAHMGLL | |
| SCHEMBL8832922 | 0.85 | SNCA (0.38) | POLBSIGMAR1CYP19A1FAAHMGLL | |
| SCHEMBL9026873 | 0.85 | SIGMAR1 (0.33) | SIGMAR1CYP19A1FAAHMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0722447-A1 | 3-PYRROLIDINYLTHIO-CARBAPENEM DERIVATIVES AND THEIR ANTIMICROBAL ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-07-24 | — | — | EP | disclosed |
| WO-1995010520-A1 | 3-PYRROLIDINYLTHIO-CARBAPENEM DERIVATIVES AND THEIR ANTIMICROBAL ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-20 | — | — | WO | disclosed |