Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 3/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | RRM1 | P23921 | 1/20 | 0.35 |
| ▸ | RRM2B | Q7LG56 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9027093 | 0.89 | LMNA (0.36) | S1PR2S1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL9025756 | 0.84 | NPC1 (0.44) | ADORA3ADORA2ACHRM2CHRM1RXFP1 | |
| SCHEMBL9025551 | 0.81 | KDM4E (0.43) | SLC6A4LMNARXFP1ALDH1A1KMT2A | |
| SCHEMBL9024526 | 0.80 | ALDH1A1 (0.33) | ADORA2ASLC6A2SLC6A4S1PR3LMNA | |
| SCHEMBL9025274 | 0.77 | SLC6A2 (0.36) | SLC6A2SLC6A4S1PR3MAOBALDH1A1 | |
| SCHEMBL9026705 | 0.76 | SLC6A2 (0.37) | SLC6A2SLC6A4S1PR2S1PR4S1PR1 | |
| SCHEMBL9026962 | 0.76 | LPAR1 (0.37) | SLC6A2SLC6A4S1PR3GAAALDH1A1 | |
| SCHEMBL9025806 | 0.74 | MAPT (0.39) | ADORA2AMAOBLMNARXFP1ALDH1A1 | |
| SCHEMBL9025673 | 0.73 | KMT2A (0.39) | MAOBALDH1A1KMT2AMAPTHPGD | |
| SCHEMBL9025095 | 0.71 | MAPT (0.38) | S1PR1MAOBMAOALMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711290-A1 | METHYLGUANIDINE DERIVATIVES, METHODS FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAID DERIVATIVES | SANOFI (FR) | 1996-05-15 | — | — | EP | disclosed |
| WO-1995004052-A1 | METHYLGUANIDINE DERIVATIVES, METHODS FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAID DERIVATIVES | SANOFI (FR) | 1995-02-09 | — | — | WO | disclosed |